neoYeast™
Discover and manufacture next-generation proteins with non-canonical amino acids
benefits
Unlocking the benefits of non-canonical amino acids (ncAA)
Longer half-life
Conjugate a broad variety of half-life-extending moieties
New functionalities
Attach small molecules, nucleic acids, and proteins
New chemistries
Optimize chemical properties to improve efficacy, absorption, or formulation
Increased stability
Constrain flexibility or block cleavage
Always site-specific
Control exactly where the protein is modified, every time
TECHNOLOGY
Enabling the discovery and manufacturing of proteins containing non-canonical amino acids
Genome-rewritten yeast (Saccharomyces cerevisiae) for high efficiency, in vivo incorporation of non-canonical amino acids into proteins
High sensitivity surface display screening and secretion for ncAA protein discovery
Single strain for discovery through to scalable biomanufacturing